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Infant Nutritional Products

Understanding and monitoring the osmolality of human milk, milk fortifiers, pediatric medications and infant nutritional products is a very relevant topic in the neonatal intensive care setting. Administration of hyperosmolar feeds in neonates has been linked to a wide variety of adverse conditions including altered nutrient absorption, hypertonic dehydration, diarrhea, intestinal ischemia, as well as more sever gastrointestinal abnormailities including necrotizing enterocolitis (NEC).  Common feeding and supplementation practices in the NICU due little to confirm the actual osmolality of individual feed samples, and in many cases can impact patient safety by increasing the risk of hyperosmolar feedings.  Many neonatal intensive care units have adopted the use of osmometry as a quality control tool to avoid incidences of hyperosmolar feedings and improve patient safety.

Download the scientific whitepaper: Practical Evaluation of Osmolality for the Evaluation of Human Milk and Infant Nutritional Products in the Neonatal Intensive Care Unit

Practical Application of Osmolality for the Evaluation of Human Milk and Infant Nutritional Products in the Neonatal Intensive Care Unit
Andrea Curria, Kelly Peterson

Learn more about Advanced Instruments research with human milk and infant nutritional products by downloading our technical whitepaper.

Advanced Instruments presents a study where common milk-medication mixtures were analyzed for osmolality using a freezing point depression osmometer. Click here to gain access to the full article.

Get the download of Milk as a Vehicle for Oral Medications, Journal of Perinatology

Milk as a Vehicle for Oral Medications: Hidden Osmoles
PG Radmacher, M D Adamkin, S T Lewis and D H Adamkin
Objective:
Once critically ill, preterm infants have transitioned to enteral or oral feedings, it is common to mix oral medications with milk feedings. The osmolality of oral and intravenous drugs were tested in the 1980s and many were found to exceed the American Academy of Pediatrics (AAP) recommended limit (400 mOsm/kg−1 H2O). Many new milks and medications have entered the neonatal intensive care unit (NICU) since then. The objective of this study was to measure the osmolality of common milk-medication combinations administered in the NICU.
Conclusion:
The coadministration of medications with milk products should be evaluated as a potential contributor to gastrointestinal intolerance of feedings in preterm infants.